Tracking the killers: how should we measure CD8 T cells in HIV infection?

نویسنده

  • Judy Lieberman
چکیده

Most immunologists agree that CD8 T cells are important in controlling viruses, at least after the first week of infection – the time it takes for naive CD8 T cells to expand and differentiate into antiviral cytotoxic T lymphocytes (CTL). Nonetheless, CD8 T-cell measurements in HIV clinical studies show little relation to disease prognosis. There are two possible interpretations – either CD8 T cells are not important in established HIV infection or we are not measuring the right things.

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عنوان ژورنال:
  • AIDS

دوره 18 11  شماره 

صفحات  -

تاریخ انتشار 2004